ATP1A2 Main Fundraising Page
$100,000 goal
This is the main fundraising page for the ATP1A2 project for Cure AHC at Duke University.
ATP1A2 is a gene which encodes the alpha-2 subunit of a protein known as a Na+/K+ ATPase. This alpha-2 subunit of the Na+/K+ ATPase is primarily found in nervous system cells called glial cells. Glial cells are scavengers of the central nervous system (CNS), and they protect neurons by scavenging the excess amount of glutamate known as the main excitatory chemical in the CNS. Since the alpha-2 subunit of the Na+/K+ ATPase is expressed in glial cells and regulates the concentration of glutamate, abnormalities in the alpha-2 subunit can cause devastating disease in humans, like familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood, and epileptic encephalopathy.
Duke University is generating a mouse model of an ATP1A2 mutation, in the hopes of developing treatment options for patients with this mutation. Cure AHC is raising funds through this page for this project, as not only will this research directly benefit those with ATP1A2 mutations, but also potentially shed light on all the cases of alternating hemiplegia of childhood (the majority of which are caused by ATP1A3 mutations.
Thank you in advance for supporting this important project to furhter research towards a treatment/cure.
ATP1A2 is a gene which encodes the alpha-2 subunit of a protein known as a Na+/K+ ATPase. This alpha-2 subunit of the Na+/K+ ATPase is primarily found in nervous system cells called glial cells. Glial cells are scavengers of the central nervous system (CNS), and they protect neurons by scavenging the excess amount of glutamate known as the main excitatory chemical in the CNS. Since the alpha-2 subunit of the Na+/K+ ATPase is expressed in glial cells and regulates the concentration of glutamate, abnormalities in the alpha-2 subunit can cause devastating disease in humans, like familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood, and epileptic encephalopathy.
Duke University is generating a mouse model of an ATP1A2 mutation, in the hopes of developing treatment options for patients with this mutation. Cure AHC is raising funds through this page for this project, as not only will this research directly benefit those with ATP1A2 mutations, but also potentially shed light on all the cases of alternating hemiplegia of childhood (the majority of which are caused by ATP1A3 mutations.
Thank you in advance for supporting this important project to furhter research towards a treatment/cure.
Thank you for your interest.
ATP1A2 Main Fundraising Page
This is the main fundraising page for the ATP1A2 project for Cure AHC at Duke University. ATP1A2 is a gene which encodes the alpha-2 subun more...
by Cure AHC,
Raleigh, NC
Created May 1, 2019
This is the main fundraising page for the ATP1A2 project for Cure AHC at Duke University.
ATP1A2 is a gene which encodes the alpha-2 subunit of a protein known as a Na+/K+ ATPase. This alpha-2 subunit of the Na+/K+ ATPase is primarily found in nervous system cells called glial cells. Glial cells are scavengers of the central nervous system (CNS), and they protect neurons by scavenging the excess amount of glutamate known as the main excitatory chemical in the CNS. Since the alpha-2 subunit of the Na+/K+ ATPase is expressed in glial cells and regulates the concentration of glutamate, abnormalities in the alpha-2 subunit can cause devastating disease in humans, like familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood, and epileptic encephalopathy.
Duke University is generating a mouse model of an ATP1A2 mutation, in the hopes of developing treatment options for patients with this mutation. Cure AHC is raising funds through this page for this project, as not only will this research directly benefit those with ATP1A2 mutations, but also potentially shed light on all the cases of alternating hemiplegia of childhood (the majority of which are caused by ATP1A3 mutations.
Thank you in advance for supporting this important project to furhter research towards a treatment/cure.
ATP1A2 is a gene which encodes the alpha-2 subunit of a protein known as a Na+/K+ ATPase. This alpha-2 subunit of the Na+/K+ ATPase is primarily found in nervous system cells called glial cells. Glial cells are scavengers of the central nervous system (CNS), and they protect neurons by scavenging the excess amount of glutamate known as the main excitatory chemical in the CNS. Since the alpha-2 subunit of the Na+/K+ ATPase is expressed in glial cells and regulates the concentration of glutamate, abnormalities in the alpha-2 subunit can cause devastating disease in humans, like familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood, and epileptic encephalopathy.
Duke University is generating a mouse model of an ATP1A2 mutation, in the hopes of developing treatment options for patients with this mutation. Cure AHC is raising funds through this page for this project, as not only will this research directly benefit those with ATP1A2 mutations, but also potentially shed light on all the cases of alternating hemiplegia of childhood (the majority of which are caused by ATP1A3 mutations.
Thank you in advance for supporting this important project to furhter research towards a treatment/cure.
Thank you for your interest.